The primary care measure for persistent epilepsy is to tilt the patient’s head to the side and remove the patient’s vomit and oral secretions so that the secretions or vomit do not cause the patient to aspirate by mistake. The patient should be protected from tongue bites and from sharp objects in the vicinity of the patient during the seizure. In addition, the patient should be given medication as soon as possible to end the status epilepticus, which can be controlled by diazepam, midazolam and sodium valproate injection. At the same time, the patient’s vital signs should be monitored, and if necessary, oxygen and dehydration medication should be given to the patient to avoid prolonged convulsions leading to brain edema and life-threatening.