Epilepsy is a common chronic disease of the nervous system, with a prevalence of about 7.0‰ and about 10 million epilepsy in China. With regular and reasonable antiepileptic drug treatment, about 2/3 of epileptic patients can control their seizures. Long-term antiepileptic drug treatment can not only bring different degrees of side effects, but also increase the burden of patients. Then how long after seizure-free patients can gradually reduce their medication until they stop is the most important concern of epilepsy patients and their families. Reasonable withdrawal of medication is important to reduce the risk of seizure recurrence, improve the quality of life of epilepsy patients, and reduce the side effects of antiepileptic drugs. The actual clinical work found that some patients with epilepsy stop their medication prematurely because they are worried about the toxic side effects of the medication, while some patients take the medication for a long time because they are worried about re-seizures, as little as 10 years or a lifetime on the medication. How soon should a person with epilepsy withdraw their medication? How to withdraw medication (i.e., how quickly it is withdrawn) should vary from person to person and should be done under the strict guidance of an epilepsy specialist.