From a clinical point of view, liver fibrosis can lead to a series of changes in liver structure and function, and patients show specific symptoms as follows: 1, fatigue and weakness: one of the most common symptoms of early liver fibrosis; 2, loss of appetite: sometimes accompanied by nausea and vomiting, mostly caused by disorders of gastrointestinal secretion and absorption during liver damage in chronic hepatitis; 3, indigestion: after eating, epigastric fullness, flatulence, constipation or diarrhea, vague pain in the liver area, etc.; 4, chronic gastritis: chronic hepatitis patients appear acid reflux, belching, erratic, epigastric vague pain and epigastric fullness and other stomach symptoms; 5, bleeding: often appear spider nevus, epistaxis, gum bleeding, skin and mucous membrane some purple spots or bleeding spots, women often have excessive menstruation.