An elderly patient who had been seen recently for four years after radiotherapy for nasopharyngeal carcinoma had not been reviewed regularly. Recently, he visited the hospital as an outpatient because he found an egg-sized mass growing on the left neck above the clavicle. However, after examination, it was found that lung metastasis had occurred and the opportunity to save the treatment was lost, which was very unfortunate! Therefore, for every patient who has finished treatment, we will hand over to make sure to review regularly. I. Why do we need regular review? Due to the progress of various medical technologies, many malignant tumors can be cured nowadays, but there are still some patients who may have recurrence or metastasis. For patients with recurrence and metastasis, if they can be detected at an early stage, such as only one lung metastasis lesion or a small recurrence at the primary site, they can fight for the chance of eradication again through surgery or radiotherapy and other means. Regular review can detect the recurrence of metastasis at an early stage and win the second life for many patients. II. What kind of clinic do I see for regular review? Patients who have finished surgery and radiotherapy should go to oncology clinic for review as much as possible. In addition, if endoscopy is needed, such as nasal endoscopy, laryngoscopy, gastrointestinal endoscopy, etc., they should be examined in related departments. How often should I be rechecked? Most of the patients, after treatment, should be reviewed once every three months within two years, once every six months from three to five years, and once a year after five years, or add a few tumor-related examinations during the annual routine physical examination. Because the peak period of tumor recurrence and metastasis is within five years, especially within two years after treatment, so close follow-up examinations are needed during this period. For example, head MRI can be done once every six months, bone scan once a year, endoscopy once every six months, lung CT once every three months for high-risk patients and once every six months for low-risk patients. What are the items to be examined in the review? (a) The parts that are prone to metastasis or recurrence. The vast majority of tumors are prone to metastasis to lung, liver and bone, and some tumors are prone to metastasis to brain. When choosing the examination methods, head and neck should choose MRI, lung should choose CT, liver should choose B ultrasound, bone should choose ECT, lymph nodes should choose enhanced CT and B ultrasound, etc. (ii) Tumor markers, such as carcinoembryonic antigen, CA199, CA125, CA153, NSE, SCC, etc. There are also some special tumor markers, such as EBV DNA for nasopharyngeal carcinoma, LDH for lymphoma, β2 microglobulin, hemocyanin electrophoresis, and urine perine protein for myeloma. (C) Other routine items, such as blood and urine routine, electrocardiogram. If you have used adriamycin chemotherapy, we suggest you to check cardiac ultrasound, if you have had head and neck radiotherapy, we suggest you to check thyroid function, if you have had chest radiotherapy, we suggest you to check lung function, etc. In conclusion, regular review should be reasonably arranged, and it is highly likely to obtain a chance of salvage treatment, which must not be taken lightly.