According to a survey, there are more than 8 million people with epilepsy in China, and about 20% of them have drug-refractory epilepsy, or intractable epilepsy, which needs to be considered for surgical treatment. So which epilepsy patients are suitable for surgical treatment? 1. Drug-refractory epilepsy: as a basic principle, epileptic patients treated with 2 to 3 major antiepileptic drugs systematically for 2 years with poor results should be considered for surgery; 2. Seizures significantly affect the patient’s daily life: if seizures affect the patient’s education, employment, and maintenance of daily living ability, especially in infants and children with frequent seizures, surgery should be considered as early as possible to organize the epilepsy The impact on the development of brain function. More consideration is given to the disabling nature of seizures, and there is no clear rule on the frequency of seizures, which is generally considered to be more than 1 seizure/month; 3. Seizures due to intracranial occupying lesions with seizures as the first symptom should be actively operated even if the patient has infrequent seizures; 4. The presence or intolerance of toxic side effects from antiepileptic drugs by the patient is also an aspect of considering surgical treatment. Contraindications and relative contraindications Chronic psychosis, primary generalized seizures, and some mild seizures with insignificant impact on life are considered as contraindications to surgery.