In China, chronic hepatitis B virus infection is the most common cause of cirrhosis, hepatitis B virus replication leads to liver damage is the main reason why chronic hepatitis B patients develop cirrhosis, once the formation of decompensated cirrhosis indicates the disease into the end stage, and irreversible lesions, will be followed by ascites, vomiting blood, liver coma and a series of serious complications, endangering the lives of patients, bringing great suffering and economic burden to patients and families. In fact, cirrhosis after hepatitis B is preventable and controllable, the author often encounters chronic hepatitis B patients in the clinic to consult how to avoid the development of the disease into cirrhosis, the following answers to this question. Scientific treatment, regular disease monitoring coupled with good lifestyle habits is the key to prevent chronic hepatitis B patients from developing cirrhosis, the author believes that hepatitis B patients to prevent cirrhosis should do the following three things: 1, first of all, scientific and standardized antiviral therapy. Hepatitis B virus is the most fundamental cause of liver damage and liver fibrosis, only antiviral therapy can inhibit viral replication, thereby reducing the damaging effect of the virus on the liver. For patients with indications for antiviral treatment should be timely and regular antiviral treatment, do not miss the best time for treatment. 2, followed by regular detailed disease monitoring. Regular monitoring can clarify their condition, chronic hepatitis B disease is very long, for most patients are lifelong carrying surface antigen, chronic hepatitis B does not necessarily require lifelong treatment, but lifelong monitoring of the disease is necessary, which is conducive to the detection of early lesions, timely intervention, prevention before it is too late; chronic hepatitis B testing includes hepatitis B two to half, liver function, hepatitis B virus quantification, liver fibrosis series, AFP, AFP, AFP, AFP, AFP, AFP, AFP, AFP. The content of chronic hepatitis B testing includes hepatitis B half, liver function, hepatitis B virus quantification, liver fibrosis series, alpha-fetoprotein (AFP), and liver aspiration pathology examination if necessary; the items and interval of examination depend on the condition. In addition, it is worth mentioning that the early symptoms of cirrhosis are not obvious, but there is a certain performance in ultrasound examination, so it is especially important for patients with a long history of chronic hepatitis B to regularly review abdominal ultrasound. 3, the last is to develop good habits in life. Good habits for the treatment and recovery of liver disease can play a good supporting role, first of all, quit smoking and alcohol, alcohol is very harmful to the liver, smoking is harmful to human immunity, and is not conducive to the regeneration of liver cells repair, all need to quit. Secondly, we should pay attention to the diet should be light, not too greasy, eat more fresh vegetables and fruits; then, life should be regular, avoid strain, pay attention to the climate change to add and remove clothes at the right time, pay attention to keep the mood relaxed, avoid the interference of bad emotions, optimistic and open-minded, positive. For patients who have developed into early cirrhosis, some of the lesions can be reversed with timely and effective treatment. However, if the cirrhosis decompensated stage, the best treatment period will be missed, so it is very important for hepatitis B patients to understand how to prevent cirrhosis.