The thrombus itself can be dissolved, but there is a clinical term for the golden hour of thrombus dissolution, which means that a thrombus can be dissolved within a short period of time after its formation, but after a certain period of time it usually cannot be dissolved and may become mechanized. A thrombus is a solid mass in the circulatory system due to an imbalance in the body’s coagulation and anticoagulation mechanisms, and can occur in arteries, veins, and capillaries. However, some clots may be mechanized and not all will dissolve on their own. If it is in the time window, operations such as thrombolysis or thrombus removal and stenting can be performed, as well as antiplatelet and anticoagulant therapy. For the acute phase of thrombosis the management is thrombolysis and thrombus removal, but there is an optimal time for treatment. In the case of arterial thrombosis, it is best to perform thrombolysis within 3 h of the onset of the disease and no later than 8 h. In the case of venous thrombosis, it is best to thrombolyze within 72 h and no later than 5 days. If a patient is diagnosed with thrombosis, he should seek medical attention in time for thrombolysis and thrombolysis within the golden time to minimize the adverse effects of the disease.