What to do after finding a meningioma

  With advances in computer technology, neuroimaging techniques have advanced rapidly, making cranial CT and MRI examinations faster, cheaper, and more accurate than ever before, making routine physical examinations available to the general population, and significantly increasing the detection rate of meningiomas. What should I do if I find out I have a meningioma?  First, don’t be nervous. Meningioma is the most common benign intracranial tumor in adults, accounting for 14.3% to 19% of primary intracranial tumors. The peak age of onset is about 45 years old, and the male s female is about 1s1.8. Meningiomas are associated with the arachnoid membrane and can occur in any part of the skull where arachnoid cells are present, especially in areas with a concentrated distribution of arachnoid granules. Meningiomas are most commonly found between the skull and brain tissue, most often adherent to the dura mater, but can also occur unassociated with the dura mater, as in meningiomas occurring within the ventricles of the brain.  Meningiomas are usually slow-growing, well-defined, benign lesions. A few can be malignant and grow rapidly. 8% of patients are multiply affected and are more common in patients with neurofibromatosis.  Second, a clear diagnosis of whether the tumor is really a meningioma Many patients have only mild headaches that have been neglected for a long time, and occasionally meningiomas are found unintentionally by CT scan during minor trauma or routine physical examination. Because of the slow growth of the tumor, it often grows very large while the clinical symptoms are not yet severe. Sometimes, the patient’s fundus optic papillary edema is already quite obvious, and even secondary optic nerve atrophy occurs, while the headache is not severe and there is no vomiting. It is worth noting that when the tumor located in the mute area grows so large that it cannot be compensated and the intracranial pressure is increased, the condition will suddenly deteriorate and even brain herniation, coma and even death will occur in a short period of time. With CT and MRI examination, the diagnosis can be confirmed in most cases.  (1) CT shows uniform lesion density with significant enhancement and wide basal attachment to the dura. non-enhanced CT scan values of 60-70 Hu are often accompanied by sandy tumor calcification. There is usually no significant cerebral edema, but a few may have significant peritumoral edema, sometimes extending to the entire cerebral hemisphere. The advantage of CT is that it can clearly show the calcification and bony changes (hyperplasia or destruction) of the tumor.  (2) MRI generally shows equal or slightly longer T1 and T2 signals. 60% of the tumors are isosignal to the gray matter on T1 images and 30% are hyposignal below the gray matter. On T2-weighted images, 50% are isosignal or high signal, 40% are moderate high signal, and may be mixed signal. The tumor is well-defined, round or round-like, and most of the edges have a low-signal band in an arc or ring shape, which is the residual subarachnoid space (cerebrospinal fluid). The parenchymal part of the tumor shows homogeneous and obvious enhancement by venous enhancement. MRI has the advantage of clearly showing the relationship between the tumor and the surrounding soft tissue. The disappearance of the subarachnoid interface between the meningioma and the brain indicates that the tumor is growing invasively, making total surgical resection more difficult.  (3) Dural enhancement at the base of the tumor may form a meningeal tail sign, which is a characteristic sign of meningioma, but is not unique to meningioma. Other lesions in the adjacent dura, such as metastatic carcinoma and glioma, may also have similar imaging features.  (4) Simultaneous CT and MRI enhancement scans and comparative analysis can lead to a more correct localization and qualitative diagnosis.  Third, find a skilled specialist for surgical treatment If long-term follow-up reveals that the meningioma has not grown significantly, surgery may also be unnecessary in a hurry. However, early surgical removal is recommended for larger meningiomas or those with more pronounced growth. Although radiation therapy such as gamma knife is effective for some smaller tumors, surgical removal of meningiomas is still the most effective treatment. With the development of microsurgical techniques, the surgical results of meningiomas continue to improve, allowing most patients to be cured. However, skilled surgical skills and sufficient patience are required to remove as much of the diseased meninges as possible under the surgical microscope in order to minimize the possibility of recurrence. For meningiomas and malignant meningiomas that cannot be completely excised, radiation therapy is required after surgery. Radiation therapy is effective for malignant meningiomas and vascular ependymal meningiomas, but care should be taken to avoid side effects such as radiation damage.