In general, blood pressure can be lowered to a safer range in about 1-2 weeks after taking antihypertensive drugs, but it also depends on the patient’s condition. Antihypertensive drugs are divided into short-acting antihypertensive drugs and long-acting antihypertensive drugs. The control of blood pressure by antihypertensive drugs is a cumulative process, usually about 1-2 weeks after taking the drug can make the blood pressure drop to a safer range, and about 2-4 weeks can be controlled at a more desirable level. In the case of patients with hypertensive crisis or malignant hypertension with blood pressure reaching 200/120 mmHg or more, this situation requires a 25% reduction in blood pressure within 4 hours and control of blood pressure to about 160/100 mmHg within 24 hours. In addition, for patients with relatively high blood pressure or concomitant underlying diseases such as coronary heart disease, two or more oral antihypertensive drugs can be combined to lower blood pressure.