After the diagnosis of epilepsy is clear, the next step involves medication. For epilepsy with sparse seizures, only 1 to 2 seizures a year or a benign prognosis, medication can be withheld. Before medication is administered, the efficacy and adverse effects of the drug need to be weighed to achieve an optimal balance for the best efficacy and the least adverse effects. For students, children, and patients with poor compliance with medication, a long-acting dosage form can be chosen and taken once daily or once in the morning and once in the evening, which makes it easier for family members to supervise. For patients with more than one seizure type or those whose seizure type is still unclear, broad-spectrum antiepileptic drugs such as Depakene, Lamotrigine, Levetiracetam, and Toltea are preferred. Antiepileptic drugs may have certain adverse reactions, which should be reviewed promptly once they occur to avoid continued aggravation of adverse reactions before seeking medical attention, leading to serious consequences. It is important to explain to patients and families that intellectual impairment and cognitive decline found during drug therapy are not exclusively adverse reactions to antiepileptic drugs, but may also be part of the natural course of concomitant disease or epilepsy. Increase education about compliance with epilepsy treatment and caution patients that the purpose of medication is to control seizures, not to cure the primary disease causing the epilepsy. Antiepileptic drugs require at least 5-6 drug half-lives to take effect. If seizures still occur within a short period of time after starting medication, do not change to another drug at will. If the preferred medication is confirmed to be ineffective, it may be prudent to combine or switch to another type of medication. Avoid stimulation by triggering factors at all times. If you also have other medical conditions, you should be aware of whether the combined medications may trigger epilepsy.