Cholinergic urticaria without sweating may be caused by localized skin congestion and swelling affecting the function of sweat glands. The onset of cholinergic urticaria is usually during exercise, heat or stress, the neurotransmitter acetylcholine will act on the mast cells in the skin tissue, which will secrete and produce some allergic substances, causing acute inflammation in the local tissues, which may sometimes affect the sweat glands in the skin, and then the patient will have the condition of not sweating. Cholinergic urticaria usually acute onset, if the symptoms of not sweating, you can follow the doctor’s instructions to take levocetirizine and other anti-allergic drugs active treatment, at the same time, pay attention to appropriate rest and avoid heat and mental stress, to prevent the cholinergic nerves continue to excitation, which will make the urticaria gradually subside, the situation of not sweating will be improved.