How to treat cavernous hemangioma in infants

  Patient: My son was born on July 18 of this year, and a spherical greenish-purple protrusion with a diameter of about 1.5 cm and an unsmooth surface was found on the left cheek of the mouth at birth. At the age of 2 months, the child went to Xinjiang Urumqi Medical College and was diagnosed with cavernous hemangioma, which was treated with local hormone injections (trimethoprim) once a week at about 0.5 mg each time. Considering that long-term injection of hormone affects the growth and development of children, surgery children also can not bear, recently often drooling will also cause infection, and will soon grow teeth, last Monday the child turned 4 months, the doctor changed to the injection of Pingyangmycin, today the child’s lips are white, and even some places ulcerated, is this drug worked, or this drug is toxic? What tests are needed to confirm the diagnosis of hemangioma and vascular malformation? Do you have any treatment methods other than surgery or local injection of the hormone Pingyangmycin that are more effective? Are we missing the best time for treatment?  Doctor: Please don’t be anxious, you have seen it in time. Spongiform hemangioma is a vascular malformation, not a real one. However, there are a few vascular diseases that require tissue biopsy to confirm the final diagnosis, but biopsy is not suitable because it can cause bleeding. Therefore, doctors can only use drugs according to their experience. Pingyangmycin is currently recognized as a better approach for venous malformations. Your child has just been injected, local whitening is still normal, it takes months to work, so please don’t rush over to Shanghai. Let’s observe it again.  Patient: Is cavernous hemangioma a vascular malformation and not a true one? The child was injected with Pingyangmycin 2mg on Monday, the tongue edge is normal, there is a small ulcer on the buccal mucosa and the corner of the mouth, today it has improved, there is no infection, the ulcerated area has healed, the affected area is no longer swollen, it seems that Pingyangmycin works well. I bought the rehabilitation solution and did not use it. I have never had a pathological examination and would like to know the exact location, size and depth of the lesion. Since the diagnosis of cavernous hemangioma has been confirmed, should we still do MRI? The child is now 4 months old and soon faces growing teeth, the affected area of the buccal mucosa is protruding from the surface, frequent contact with the teeth is worried that it will cause bleeding and infection, the color of the lips does not change later it does not matter, the edge of the tongue and the buccal mucosa probably need to be injected for how long Pingyangmycin can be cured? The child is 9kg now, how much dose should be injected each time? How long is the interval between injections?  Doctor: Don’t do pathological examination. the MR time is too long for children is not very good to do. Don’t worry too much about the teeth either, they usually don’t rub and bleed. It is recommended to observe at least three months before dealing with it.