Diabetes mellitus is genetically susceptible, and there is no evidence to suggest whether it is easily inherited from daughters or sons. Diabetes mellitus is a group of metabolic disorders characterized by chronic hyperglycemia due to multiple etiologies and is caused by defects in insulin secretion and/or utilization. Diabetes mellitus is affected by a variety of factors such as genetic predisposition, environmental factors, and lifestyle habits. The etiology and pathogenesis of diabetes are extremely complex and have not been fully elucidated to date. The etiology varies from type to type, and even within the same type there is heterogeneity. In general, both genetic and environmental factors are involved in the development of diabetes. If parents have diabetes, children should participate in physical exercise, control their weight, monitor their blood glucose regularly, and improve their living environment to prevent the development of diabetes.