After the healing of severe burns, the skin will be scarred, and the scar will form a chronic non-healing wound if it breaks repeatedly. This chronic non-healing wound, due to inflammatory stimulation and other factors such as repeated proliferation, has the possibility of malignant transformation, and most of this malignant tumor is squamous cell carcinoma, which is relatively low in malignancy and has a low probability of bloodstream metastasis, which is relatively less harmful to the body. Paget \\”s disease is a malignant tumor that appears in the areas rich in sweat glands such as breast, genitalia, scrotum, anus and axilla. In this case, a middle-aged male with a peanut-sized hot oil burn on his forearm 9 years ago, formed scar hyperplasia after healing, and developed itchy and painful changes 2 years ago, and was admitted to the hospital for scar excision and suturing. It has never been reported internationally. In this article, we analyze the family history of the diagnosis and treatment of scar hyperplasia evolving into Paget \\”s disease.