Vogt-Koyanagi-Harada syndrome (VKH) is a disease with meningeal irritation signs, hearing impairment, vitiligo, and hair whitening or loss, characterized by bilateral total uveitis, also called “uveal cerebritis”. Clinical manifestations Before the onset of the disease, there are mostly cold-like or other prodromal symptoms, which manifest as headache, otorrhea, hearing loss and scalp allergy and other changes. Later, there is a sudden loss of vision in both eyes, and examination reveals a late-onset fundus, optic discitis, retinal edema in the posterior pole, and even plasmacytoid retinal detachment. In addition to the above manifestations, extraocular changes such as alopecia, hair whitening and vitiligo may also occur. Common complications include complicating cataract, secondary glaucoma and exudative retinal detachment. Diagnosis Diagnosis is based on the typical history and characteristic changes. Fluorescein fundus angiography is helpful for diagnosis. Treatment Prednisone is mainly given orally for the first episode, usually with an initial dose of 1-1.2 mg/(kg・d), which is started to be reduced in 10-14 days, with a maintenance dose of 15-20 mg/d (adult dose), and treatment mostly takes more than 8 months. For patients with relapse, other immunosuppressive agents should generally be given. Second, sympathetic ophthalmia sympathetic ophthalmia No./N-uveitis – 49 Section II several specific types of uveitis vogt.,b杉li Harada syndrome Vogt a small Yanagi Harada syndrome (Vogt-Koyanagi- HaradaSyndrone (VKH) is a disease characterized by bilateral total uveitis with signs of meningeal irritation, hearing impairment, vitiligo, and hair whitening or loss, also known as “uveal encephalitis”.