Ischemic necrosis of the femoral head combined with medullary decompression and stem cell transplantation – Green Medicine for Bone and Joint Diseases Aseptic necrosis of the femoral head, or ischemic necrosis of the femoral head, is a type of osteonecrosis. Osteonecrosis is caused by damage to the trophoblastic blood vessels of the bone due to a variety of causes, which further leads to ischemia, degeneration, and necrosis of the bone. The disease can occur at any age but is most common between the ages of 20 and 60, with no gender differences. It starts with vague or dull pain in the hip joint or its surrounding joints, which is aggravated by activity, and further development can lead to dysfunction of the hip joint, seriously affecting the patient’s quality of life and ability to work, and can also lead to lifelong disability if not treated in time. Early signals and etiology, the following points should be noted: (1) Hip and knee pain, also known as ectopic pain, is the main manifestation of early ischemic symptoms of the femoral head, which is often overlooked because it is “far” from the hip joint and easily misdiagnosed as arthritis or joint injury, but is actually a radiological symptom related to femoral head necrosis. This pain can be obvious due to exertion, trauma, heavy alcohol consumption, excessive activity, going up and down stairs and other triggers. (2) Children aged 3-10 years old with a history of minor trauma or upper sensation before the onset of the disease. Sudden onset, the child refers to knee joint and inner thigh detection pain, which turns into hip pain after a few days, and later causes lameness, not high temperature and low fever, hip joint has pressure pain, the affected hip is maintained in slightly flexed and adducted position, hip joint internal rotation and abduction activities are obviously limited, the affected hip joint photo contrast, epiphysis and cartilage surface is not smooth. (3) Patients treated with steroid drugs for skin diseases (such as psoriasis, polymorphic erythroderma, etc.) can slow down the synthesis of osteoid in osteoblasts, hinder the transformation of preosteoblasts to osteoclasts, affect the absorption of calcium from the intestine, and develop osteoporosis. Subtle fractures of bones can occur after trauma, and the antagonistic force is reduced, causing bone compression or collapse. Due to compression of marrow cells and capillaries, obstruction of blood flow can lead to osteonecrosis, and if it occurs in the femoral head, it is osteonecrosis of the femoral head. When you find limping when walking, alleviated after rest, and hip discomfort or soreness when sitting down, most of the tips should be alert to this disease. (4) Hyperlipidemia, which occurs after long-term excessive alcohol consumption, is increasing. According to statistics, men who drink more than 250 grams (half a city pound) of alcohol per day will have elevated free lipic acid in the blood, which can lead to vascular embolism in the bone and eventually lead to osteonecrosis. The early feeling of hip and knee pain, especially at night or after exertion, sometimes feel pain in the inner thighs or knee joints, mostly diagnosed as rheumatic disease. This abnormal sensation is the early stage of “hip coronary artery disease”, and delayed treatment may cause irremediable disability sequelae. Surgical treatment of early ischemic necrosis of the femoral head is an important tool to prevent the development of advanced lesions and the need for artificial joint replacement. The choice of early treatment and prediction of outcome are important for prognosis. The traditional treatment method is the medullary decompression technique based on the ring drilling method. We use autologous bone marrow stem cell transplantation to provide a new and more effective treatment route for early ischemic necrosis of the femoral head. Stem cell transplantation for ischemic necrosis of the femoral head is based on the principle that stem cells and endothelial progenitor cells can differentiate into vascular endothelial cells and form neovascularization, and stem cells and endothelial progenitor cells from the patient’s own bone marrow or peripheral blood are isolated and transplanted into the ischemic femoral head lesion to gradually differentiate and form new capillaries, promote vascular regeneration, improve and restore blood flow in the lower limbs, and achieve the goal of treating The purpose of treatment of femoral head ischemia. The highly directed differentiation ability of hematopoietic stem cells can promote the formation of new blood vessels, fundamentally solving the problem of blood supply to the femoral head and preserving the integrity and function of the femoral head. The procedure is simple, does not require more equipment, and has good application prospects. Therefore, bone marrow stem cell transplantation for early ischemic necrosis of the femoral head has positive clinical significance in promoting the recovery of the necrotic area.