As we get older, many elderly people may gradually develop hypertension, and 90% of patients have primary hypertension, which means that the blood pressure rises for unknown reasons or due to family genetic reasons. The best treatment for primary hypertension is oral antihypertensive medication. In addition to antihypertensive medication, we recommend that patients take secondary prevention medications that can prevent further progression of the disease, so that the disease can be better controlled and prevent complications of hypertension. It is recommended that elderly people try to choose first-line, long-acting antihypertensive drugs, first-line long-acting antihypertensive drugs mainly include beta-blockers, calcium channel blockers, ACEI/ARB, diuretics, etc. Beta-blockers, representative drugs are metoprolol, bisoprolol and so on. These drugs have a relatively weak antihypertensive effect and are mainly used in clinical settings as an adjunct to hypertension, because in addition to lowering blood pressure, beta-blockers can also slow down the heart rate, prevent left ventricular remodeling, reduce myocardial oxygen consumption, and prevent the occurrence of coronary heart disease and angina pectoris. Therefore, for patients with hypertension, it is recommended to take this drug in combination as long as the heart rate can be tolerated. ACEI/ARB, representative drugs include enalapril, irbesartan, etc. These drugs can also prevent left ventricular remodeling and improve myocardial ischemia, and are very suitable for patients with hypertension, with diabetes or hypertension with renal impairment. Calcium channel blockers, such as nifedipine extended-release tablets and felodipine, can help prevent platelet aggregation while lowering blood pressure, and are also very suitable for elderly patients with hypertension. Diuretics, representative drugs include hydrochlorothiazide and zinospirolactone, spironolactone can prevent vascular remodeling and is a secondary prevention drug for heart failure patients. Hypertension can accelerate the progression of atherosclerosis, so elderly patients taking antihypertensive drugs are also recommended to take a combination of bai aspirin, which helps antiplatelet and anti-atherosclerosis. However, the application of aspirin must be remembered to be combined after the blood pressure has stabilized. Along with the application of aspirin patients are also recommended to take a combination of oral statins, which help to improve vascular endothelial function, stabilize plaque, and lower lipids.