There are two kinds of hand numbness during sleep, one is near the thumb side, especially the numbness of the thumb, index finger and middle finger, and the other is near the little finger side, usually the numbness of the little finger and ring finger. Both types of numbness may occur during sleep. If the numbness is near the thumb side is often carpal tunnel syndrome, which is caused by compression of the median nerve in the wrist area, you can shake your hand after waking up from numbness, and the numbness will gradually ease after shaking your hand. The numbness of the little finger is often caused by the elbow canal syndrome, which is often caused by flexion of the swollen joint during sleep, which stretches the middle ulnar nerve at the back. Whether it is elbow or carpal tunnel syndrome, the diagnosis can be confirmed by electromyography. At the beginning, numbness in the hand can be treated conservatively with oral or intramuscular nerve medication. If there is no effect, surgery should be performed as soon as possible to release the compression of the nerve in order to relieve hand numbness.