After mitral mechanical valve replacement, if there is a secondary thrombosis in the left ventricle, it can be treated with medication or interventional surgery. 1. Medication: Once thrombus is formed in the left ventricle, medication can be considered first. According to the specific condition and past medical history, medication such as double antibiotic (e.g., aspirin, clopidogrel), factor Xa inhibitor (e.g., rivaroxaban), and vitamin K antagonist (e.g., warfarin), etc., can be used under the guidance of specialized doctors. 2. Interventional surgery: If the thrombus dislodges into the peripheral circulation, it may cause systemic circulatory disorders, which can be treated by interventional surgery, such as thrombectomy or filter implantation, to ensure normal circulation. Left ventricular thrombosis is a common postoperative complication of mitral valve valve replacement, once it occurs, it should go to the hospital in time, under the guidance of professional doctors for standardized treatment.