Misoprostol tablets have a good safety profile and serious adverse reactions are rare. During use, observe the changes in body temperature, blood pressure, pulse rate and adverse reactions such as nausea, vomiting, diarrhea, dizziness, abdominal pain, itching of the palms, drug allergy, etc. Be alert to serious adverse reactions such as anaphylaxis and laryngeal edema, and provide immediate symptomatic treatment for those with more severe symptoms. Also closely observe bleeding and fetal and placental expulsion [1]. Any active bleeding before or after the elimination of pregnancy products should be treated in the emergency room. Among the above-mentioned adverse reactions abdominal pain and diarrhea are dose-related and also self-limiting. The risk of diarrhea may be reduced by not exceeding 0.2 mg in a single dose with food and by avoiding antacids containing magnesium if antacids are required. Special attention should be paid to the FDA drug insert warning that the use of this drug in women during pregnancy can lead to birth defects, miscarriage, preterm delivery, and reports of uterine rupture due to induction of labor or abortion. Therefore, women of childbearing potential should not be treated with misoprostol tablets until pregnancy has been ruled out and must use effective contraception during the course of treatment. If pregnancy is suspected, discontinue treatment with this drug immediately.