Having urticaria does not affect life expectancy and can lead to long-term survival. Urticaria is an allergic disease in which an allergic substance induces the body to produce IgE, which binds to the corresponding receptors on the surface of mast cells and basophils, leaving the body in a state of sensitization to the allergic substance, and when the same allergic substance enters the body again, by binding specifically to the antibodies on the surface of the sensitized mast cells or basophils. A series of biologically active substances such as histamine are released, causing dilation of small blood vessels, increased permeability, smooth muscle contraction and increased glandular secretion, resulting in a series of local or systemic allergic reaction symptoms in the skin, mucous membranes, respiratory and digestive tracts. The disease is usually characterized by a rapid appearance and fading, with the outbreak subsiding within 2-3 hours, allowing the skin surface to return to normal. After the outbreak subsides, the skin surface is consistent with normal skin, and no pigmentation abnormalities generally remain. When you have hives, it is best to go to the hospital and use desensitizing drugs for oral treatment under the guidance of a doctor. If the itching is obvious, you can also use topical medications such as stove glycolic lotion to relieve the itching symptoms.