The number of times of radiofrequency ablation of liver single tumor is not specified clinically, and the specific number of times is related to the number of recurrence of patients. Radiofrequency ablation is a kind of treatment of arrhythmia by inserting electrodes into the lesion area through the channels of femoral artery, internal jugular vein, subclavian vein, etc., and making use of the electrode at the tip of the large head catheter to form a resistive electro-thermal effect within the tumor tissues, so that the tumor cells will be dried up and necrotic, and thus achieve the purpose of treating arrhythmia. For a single liver tumor, there is no limit to the number of radiofrequency ablation treatments as long as it is recurrent and single. If the tumor is in one liver lobe, radiofrequency ablation can be considered, and local interventional chemotherapy can also be considered. For the diagnosis of single liver tumor, standardized treatment should be carried out as early as possible to reduce the adverse effects of the disease through “early detection, early diagnosis and early treatment”.