Tuberculosis is an infectious disease of the respiratory system caused by infection with Mycobacterium tuberculosis. Tuberculosis itself does not cause joint pain. The most common are large joints, such as the knee, hip and vertebrae, and can be clearly identified by X-ray arthrograms and CT scans of the joints. 2, joint pain caused by taking pyrazinamide during the treatment of tuberculosis, pyrazinamide can inhibit the growth of tuberculosis bacteria, but has a certain nephrotoxic effect in the anti-tuberculosis, which can inhibit the excretion of uric acid by the renal tubules, thus causing an increase in uric acid in the blood, resulting in Gouty arthritis, with symptoms of joint pain, requires discontinuation of pyrazinamide. Therefore, pulmonary tuberculosis with joint pain should be promptly identified as the cause and targeted treatment should be taken.