Chest pain during tuberculosis medication may be due to the following reasons: 1. Tuberculous pleurisy, patients with respiratory-related chest pain can improve lung CT for clear diagnosis. If the patient is suffering from severe pain due to tuberculous pleurisy, he can take oral pain medication, such as depot tablets, loxoprofen sodium, ibuprofen extended-release capsules, etc. At the same time, anti-tuberculosis medication should be given, such as isoniazid, rifampin, pyrazinamide, streptomycin, etc. 2. Malignant tumors of the lung, which can show symptoms of chest pain, can be clearly diagnosed by perfecting lung CT and bronchoscopic puncture biopsy.