Hyperthyroidism, or hyperthyroidism for short, is a thyrotoxicosis caused by excessive production of thyroid hormones by the thyroid glands themselves. Its causes include diffuse toxic goiter (Graves’ disease), nodular toxic goiter, and autonomic hyperfunctioning adenoma of the thyroid gland. More than 80% of these hyperthyroidism is caused by Graves’ disease. Graves’ disease is an organ-specific autoimmune disease with a significant genetic predisposition, with a risk of 11.6% for siblings and a high concordance rate for monozygotic twins. Graves’ disease has been found to be a complex polygenic disease. Also, environmental factors such as bacterial infections, sex hormones, and stress are involved in the development of the disease. And infectious diseases are infectious and can cause epidemics under certain conditions by pathogenic microorganisms, such as viruses, chlamydia, rickettsia, mycoplasma, bacteria, fungi, spirochetes, and parasites, such as protozoa, worms, and medical insects that infect humans. And the epidemic of infectious diseases requires three basic conditions: infectious source, transmission route and susceptible population, which must exist at the same time. As mentioned above, hyperthyroidism does not meet the conditions of an infectious disease, nor does it meet the conditions of an epidemic, so it is not contagious. However, hyperthyroidism has a genetic predisposition, so family clustering may occur.