If it is a small seizure, generally do not need special rescue, but when a major seizure should take measures, as follows: 1, when the patient has a dental closure, you should put the tongue depressor or take a substitute, such as chopsticks, wrapped in gauze or wrapped in a handkerchief, placed between the upper and lower teeth on one side. Prevent tongue bite; 2. Loosen the collar and belt to facilitate the smooth flow of the airway, avoid collision of limbs to avoid bruising, and support the body so as not to fall and hurt the head or break bones; 3. If the seizure stops, the patient should immediately lie on his or her side to keep the airway open, and keep him or her in a quiet and comfortable environment with air circulation around him or her; the persistent state should be resuscitated urgently. The seizure should be terminated as soon as possible, and if no drugs are available, acupuncture points sensitive to pain such as Renzhong and Yongquan can be used first. If conditions allow, it should be the early administration of antiepileptic drugs. The first time the antiepileptic drug is given, it must be in sufficient quantity, intravenous injection is better, if it is not possible, intramuscular injection is also possible. The most commonly used drugs are Valium, which can be used repeatedly until the seizures are controlled, and the maintenance dose can be given once the seizures are controlled to avoid recurrence. In addition, for some patients in a coma with persistent status epilepticus, it is necessary to prevent hypoxia, timely aspiration, etc. If necessary, tracheal intubation can be used for respiratory support. Patients with high fever should be given physical therapy, and the airway should be well protected to prevent lung infection, and the other is the treatment of some complications. Once a persistent status epilepticus occurs, it should be promptly treated in the hospital and, if necessary, in an intensive care unit.