If it is a lipoma deep in the body, or if the lipoma is repeatedly rubbed or irritated, there is a possibility that it may become cancerous, but it is less likely.
Lipoma is a benign lump formed due to the overgrowth of fat cells, most of which will not cause any pain or other symptoms, and it is a common disease in clinic, and will rarely become cancerous.
However, if the lipoma undergoes repeated friction and stimulation over a long period of time, it may lead to repeated cell proliferation, or if the lipoma is deep in the body, there is a possibility of malignant transformation, but this possibility is very small.
Lipomas usually do not require treatment, but they may need to be surgically removed if they are large or are getting larger, or if they are causing symptoms, such as pressing on nerves or obstructing the intestines.
If a patient notices that a lipoma has suddenly become larger, it is advisable to seek medical attention and have it surgically removed to prevent malignant changes.