The incidence of polycystic ovary syndrome (PCOS) is as high as 5-10%. The pathogenesis is not yet confirmed, but studies have found that it is associated with abnormal insulin metabolism, high androgens in women, and high insulin in obese women. The main effects of this disease include: (1) menstruation and reproductive function. (2) Glucose and lipid metabolism. PCOS is a chronic disease that affects women almost throughout their lives and is not curable, but can be managed. Immediate risks: including menstrual disorders, infertility, acne, hirsutism, obesity, etc. Obstetric hazards: 2 times increase in miscarriage rate, 3 to 4 times increase in incidence of gestational diabetes and gestational hypertension. Long-term hazards: including increased incidence of endometrial cancer, diabetes, metabolic syndrome, cardiovascular diseases, etc., which come insidiously and have serious consequences! Second, the need for long-term management Because of the far-reaching impact of the disease on women’s health, the disease requires long-term management. The immediate goals of long-term management are to adjust the menstrual cycle, treat hirsutism, and acne, control weight, and assist with fertility; the long-term goals are to prevent endometrial cancer, prevent diabetes, cardiovascular disease, etc. Long-term management of PCOS includes regular testing, development of a reasonable treatment plan, and timely adjustment of the treatment plan according to the situation, and long-term management should last a lifetime. Regular testing (1) what to test: testing indicators include hormones (FSH, LH, PRL, T, E2, SHBG, etc.), glucose metabolism (OGTT, INS release test), lipid metabolism, changes in liver and kidney function, etc.; (2) when to test: testing before treatment is aimed at developing individualized treatment plans; testing once every 3-6 months during treatment to understand the effects of treatment; testing before pregnancy to determine whether (2) When to test: The purpose of pre-treatment testing is to develop an individualized treatment plan. Individualized treatment plan: Since PCOS patients are highly heterogeneous and each patient has different performance, individualized treatment is needed according to each individual’s situation and requirements. 1. lifestyle modification: including exercise, diet adjustment, stress reduction, regular life, etc., which can help restore ovulation and menstruation and prevent cancer, metabolic disorders and other long-term complications; 2. androgen lowering: oral contraceptives (OC) are preferred, as well as spironolactone and dexamethasone; 3. progestins: used for those with less severe hyperandrogenic symptoms and regular retreats to protect the endometrium from cancer; 4. insulin resistance treatment: metformin is preferred. 5, infertile patients: need to go to the hospital first outpatient testing of sex hormones to the normal range and then perform prolotherapy, if there is still no pregnancy after 6 cycles of prolotherapy, IVF can be considered. 6, the appropriate time to adjust the treatment plan: PCOS patients treatment must take into account the different age stages, different requirements, different disease stages and other issues to adjust the treatment plan. 7, adolescent patients should pay attention to their specific stage of physiological Kaohsiung, unless androgens are particularly high does not recommend excessive intervention; 8, no reproductive requirements of the treatment process of regular testing of the efficacy to determine whether to stop, continue treatment, or adjust the program; 9, there are fertility requirements of the control of hormonal and metabolic disorders as soon as possible to promote ovulation to facilitate pregnancy; 10, women of childbearing age to complete the reproductive plan still need regular testing and treatment; 11, postmenopausal women still need to pay attention to the occurrence of metabolic disease Postmenopausal women still need to pay attention to the risk of metabolic diseases, and should be tested regularly and treated timely. Although PCOS is complex, variable and affects the whole life, but you must not be afraid, optimistic face positive control!