Liver metastasis of rectal malignant tumor indicates that it is already in advanced stage, and most of them will have a series of symptoms, such as cancer pain, jaundice, malnutrition, ascites and so on, and thus will be very painful. 1. Cancer pain: cancer pain is one of the most important factors affecting the quality of life of patients with advanced cancer, and most of the advanced cancer patients will have different degrees of cancer pain, and they may need to use long-term analgesic drugs to maintain the treatment, for example, morphine, codeine, oxycodone and so on. 2. Jaundice: gradual increase of liver metastasis of rectal malignant tumor can seriously affect liver function, which leads to bilirubin metabolism disorder, and jaundice symptoms such as yellow staining of skin and mucous membrane and itching will appear. 3. Malnutrition: rectal malignant tumor metastasis to the liver can cause liver nutrition and metabolism dysfunction, digestion and absorption disorder. In addition, persistent severe pain will seriously affect patients’ appetite, resulting in insufficient nutritional intake. As a result, patients with advanced stage will have different degrees of malnutrition or even malignant disease. 4. Ascites: when rectal malignant tumor liver metastasis can form abdominal fluid, especially when combined with extensive intra-abdominal metastasis of the tumor, a large amount of ascites may appear, resulting in respiratory distress and other symptoms. Liver metastasis of rectal malignant tumor in the late stage will be very painful, it is recommended to go to the hospital as soon as possible, to be treated accordingly, as far as possible to alleviate the pain and improve the quality of life.