Domestic PCOS treatment strategies and protocols are still not uniform. At present, the treatment of PCOS is mainly based on the patient’s age, the degree of lesion and the purpose of consultation and different treatment measures are taken. Prevention and treatment should be combined, advocating comprehensive, individualized and systematic treatment. 1, the establishment and promotion of PCOS primary prevention system: research shows that for obese PCOS patients, just a simple weight loss can significantly improve the endocrine and metabolic indicators of PCOS patients, 50% of PCOS patients can resume ovulation and conception on their own. The primary prevention program mainly includes lifestyle modification, such as establishing a regular rhythm of life, reasonable dietary structure and caloric intake, active weight control, participation in physical exercise, and avoiding long-term mental stress. Knowledge dissemination and behavioral interventions can be provided to patients through clinical and maternal and child health care systems at all levels of obstetrics and gynecology, with on-site guidance and interactive websites. 2. Regulation of menstrual cycle and prevention of endometrial hyperplasia: Regular and reasonable application of drugs to counteract the effects of estrogen and control the menstrual cycle is crucial to the prevention of endometrial hyperplasia and even endometrial cancer. Mostly, post-progestational semi-cycle therapy or full cycle therapy with oral contraceptives is used. It is important to check the endometrial condition regularly. 3. Anti-androgen therapy: Since high androgens in PCOS patients are not a single source, comprehensive anti-androgen therapy should be used to correct excessive androgen levels to facilitate the success of ovulation treatment. The main drugs are cyproterone acetate, spironolactone, flutamide, finasteride, etc. Because of their different mechanisms of action, they should be considered when choosing them. 4.Treatment of IR: The main application of insulin sensitizers, mainly dimethyldiphenhydramine and profibrotide, can increase insulin sensitivity and improve IR through different mechanisms of action. However, phosphoinositides are class C drugs, and their toxic effects on the liver should be noted, so the indications should be strictly controlled when applied. 5, the treatment of patients with fertility requirements: (l) drug therapy: clomiphene constitution rafters is still the first choice for ovulation in patients with PCOS. gn, such as urinary sex hormone (hMG), follicle stimulating hormone (FSH) and other ovulation effect are better, but need to pay great attention to ovarian hyperstimulation syndrome (OHSS) and the occurrence of multiple pregnancies. LETROZOL is a selective non-chisel aromatase inhibitor, which induces ovulation by inhibiting or inactivating peripheral aromatase, reducing estrogen levels and enhancing Gn secretion in a feedback manner. At present, the treatment of PCOS with letrozole is still in the experimental stage, and its efficacy, indications and safety are yet to be verified. (2) Minimally invasive treatment of PCOS: In the past decade or so, laparoscopic ovarian perforation has been widely used in the treatment of PCOS, but its long-term complications, such as pelvic adhesions and ovarian function damage, have received increasing attention, and therefore, it is advocated to be used only for patients with refractory PCOS. Ultrasound-guided immature follicular puncture as a new and effective minimally invasive treatment technique has been used in clinical practice and has received better efficacy cabinet. (3) Assisted reproductive technologies: In vitro fertilization and embryo transfer (WF-ET) and in vitro maturation of immature oocytes (IvM) are often used as the last option for patients with PCOS infertility. However, the safety and long-term effects of these new assisted reproductive techniques (e.g., IVM) on the offspring have yet to be verified by extensive clinical practice. 6, prevention and treatment of long-term complications: various long-term complications of PCOS cannot be ignored, including type 2 diabetes, hypertension, hyperlipidemia, cardiovascular disease, gestational diabetes, gestational hypertensive disorders and some malignant lesions, such as endometrial cancer, etc. called. The prevention of complications, the implementation of interventions is a long-term process, including behavioral interventions, early drug treatment, long-term follow-up observation, etc. Early diagnosis of PCOS, timely initiation of appropriate treatment, together with publicity and education, weight control, lifestyle modification and regular follow-up are important to prevent the occurrence of long-term complications. In conclusion, on the basis of evidence-based medicine, popularizing education, standardizing the diagnostic steps of PCOS and selecting individualized treatment plans should attract our high attention.