The main concern of fracture patients is when will my bone grow, and once the clinical diagnosis of non-healing fracture is made, it is a big blow to the patient, which no one wants to encounter, doctors or patients. But if it occurs, we have to find a way to face it. Here, I would like to introduce to the patients what should be done when a fracture does not heal? The first thing to do is to find out what causes the fracture not to heal and take different approaches for different causes. There are many reasons for fracture non-healing, broadly speaking, the following: 1. heavy original injury, open injury, fracture comminution, resulting in serious local blood damage 2. conservative treatment, poor reset, unstable fixation, fracture difficult to heal 3. the patient’s own health status (malnutrition, osteoporosis, etc.) 5. wound infection 6. surgery-related factors, inappropriate selection of internal fixation, poor reset, large surgical stripping, etc. In clinical work, we also classify fracture non-union into atrophic, malnutrition, hypertrophic and infected fracture non-union. Atrophic and dystrophic fractures are of poor hematopoietic and ischemic type. The main problem is that the fracture is not fixed strongly and the fracture site is too active to heal, so the treatment should strengthen the fracture site, and whether or not bone grafting is not critical. Atrophic nonunion Hypertrophic nonunion Infected fracture healing has been a problem for orthopedic surgeons and a hot topic of research, and there are many treatment options. Regardless of the treatment approach, thorough debridement is fundamental. Only when the infected bone and soft tissue are removed together can the conditions be created for the next step of treatment. I will also write a separate article for infected fractures that do not heal, which will be described in detail. I would like to say to my patients that no one wants to have a non-healing fracture, just like the patient, but the fracture healing process is a complex, long and continuous process, and a problem in one of the components can lead to non-healing. Various treatments are available, but most “friendly” fractures can be cured if the cause is found and the principles of treatment are mastered.