Hospitalization is necessary for high-risk patients with primary thrombocythemia who have significant symptoms, are older than 60 years of age, or have a history of cardiovascular disease. Avoid life-threatening symptoms such as bleeding, thrombosis, and splenomegaly. Patients with primary thrombocythemia are often associated with altered platelet morphology and function, making them more susceptible to thrombosis, embolism and bleeding. 1. Low-risk asymptomatic patients with primary thrombocythemia who are younger than 60 years of age and have no history of cardiovascular disease do not require treatment. 2. High-risk patients older than 60 years of age or with a history of cardiovascular disease, on the other hand, require active hospitalization due to the high risk of thrombosis and bleeding. Most high-risk patients with primary thrombocythemia progress slowly, and those with recurrent bleeding or thrombosis have a poorer prognosis. Some patients with primary thrombocythemia have the potential to transform into other types of myeloproliferative tumors and have a poor prognosis if the disease progresses, so patients are advised to actively cooperate with their doctors.