Young people with primary thrombocythemia can be categorized into asymptomatic and symptomatic, with the former using follow-up observation, and the latter treatment including general treatment, medication and so on. 1. General treatment: rest, control physical activity, quit smoking and drinking. 2. Drug therapy: choose hydroxyurea, routinely use aspirin; also can choose anagrelide and recombinant interferon, the former can inhibit the maturation of bone marrow megakaryocytes, the latter can inhibit the clonal proliferation of abnormal megakaryocytes. Primary thrombocythemia, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor for standardized treatment, the above drugs need to be used under the guidance of the doctor.