Some information suggests that the source of the novel coronavirus is most likely wild animals. Research reports from several scientific research groups at home and abroad have pointed out that the most likely source of the novel coronavirus is the wild bat Chinese chrysanthemum-headed bat, but only the homology of the related virus is speculated, and there is no definite evidence to confirm. Experts and scholars are still working to identify the natural and intermediate hosts of the novel coronavirus, which will facilitate the control of the source of infection and the study of therapeutic drugs, and may provide some theoretical basis for the clinical prevention and treatment of this virus infection.