Whether a boiling water blister will heal on its own without picking it up needs to be analyzed on a case-by-case basis and cannot be generalized. If the blister is relatively small and the symptoms are mild, the blister will usually be absorbed by the body’s tissues and heal itself in a week or so. If the burns are extensive and the blisters are large and affect normal life, they will not heal on their own if they are not punctured. The contents of the blisters need to be pumped out or punctured with sterile gauze under strict disinfection to protect the wound and promote healing. If the blisters are large and fused between them, the exuded plasma denatures within the blister fluid and becomes jelly-like. Under the infection of external colonizing bacteria, it is easy to form subcutaneous pus and fluid, which aggravates the infection and is not conducive to wound healing. Patients with burns should not apply drugs on their own, but should go to the hospital dermatology department for treatment in a timely manner, pay attention to protecting the trauma, do not get wet, eat a light diet, avoid eating spicy and stimulating food, and refrain from smoking and alcohol.