Whether a blister from an oil burn will go away on its own without picking it depends on the size of the blister. If the blisters are small, they can usually heal on their own without picking. However, if the burn is large and the blisters become fused, especially if the burn is deeper than degree II, the skin of the blister needs to be cut and the blister drained. Because the exudate in such large blisters is not absorbed for more than 24 hours, the oozing plasma will be denatured in the vesicular fluid and become jelly-like and cannot be completely absorbed, and may form subcutaneous pustules and effusions under the infection of external colonizing bacteria, aggravating the infection and detrimental to the healing of the wound. Therefore, if the oil scalded blisters are large, you need to go to the hospital under close disinfection, use a sterile syringe to draw out the liquid, and cover it with sterile gauze, in order to protect the wound and avoid secondary damage and contamination. In addition, usually need to pay attention to good protection when frying, once the oil droplets splash, need to timely detach from the source of scalding, and use cold water to continue to rinse the affected area or icy water immersion, in order to avoid heat on the body to cause further damage.