The transsphenoidal approach for pituitary tumor resection is divided into the following key steps: i. Clean the nasal cavity after general anesthesia, separate the nasal septal mucosal flap, and expose the bony nasal septum. Second, bite away the bony nasal septum, expose the pterygoid mouth, and find the opening of the pterygoid sinus. Third, fully grind away the anterior wall of the pterygoid sinus and separate the pterygoid sinus separation until the saddle base is revealed. 4.After grinding drill and thinning the saddle base bone, bite the bone of the saddle base with biting forceps, and avoid damaging the internal carotid artery. V. Open the dura of the saddle base to reveal the tumor. If necessary, endoscopy can be used to ensure that no tumor remains in each corner. Repair the septum and dura of the saddle base respectively. The nasal septum was repositioned, the nasal septum mucosal flap was sutured, and aspirating tampons were placed in both nostrils.