How is single nostril transsphenoidal approach therapy used to treat pituitary tumors?

Pituitary adenoma is a benign adenoma, which is quite common, and the incidence of the disease has been found to be about 1 per 100,000, with women of childbearing age predominating.

Single nostril transsphenoidal approach is currently the preferred route for the treatment of pituitary adenoma, and its features and advantages are as follows: 1. No surgical scar on the face.

2. Short surgical operation route. Although the distance from nostril to saddle base of single nostril approach is longer than that of septal sinus approach, the nasal cavity is a natural cavity and can reach the nasal base. The real surgical operation starts from fracturing the nasal septum 5-10mm from the root of nasal septum, and chiseling the anterior wall of butterfly can look directly at the saddle bottom.

3.The probability of cerebrospinal fluid leakage and optic nerve damage is smaller.

4.It is conducive to complete resection of tumor. The single nostril approach is facing the saddle base, the radiation surface on the saddle is larger, and the nasal base end of the nasal speculum can be moved so that the anterior and posterior parts of the saddle base can be well exposed. By adjusting the magnification and focal length of the nasal speculum and microscope, the single nostril approach can be used to view the tumor clearly from multiple angles and levels, which is conducive to complete resection of the tumor, reduce the damage to the supra-anterior saddle tissue and arachnoid capsule and decrease the incidence of postoperative cerebrospinal fluid leakage.

5.It is conducive to the protection of the residual pituitary function.

6.Short operation time, quick recovery, no incision and no suture.

7.But due to the narrow operating space, this requires the surgical operator to have in-depth study of anatomical knowledge and rich microscopic surgical skills and experience, to accurately grasp the indications and contraindications of surgery, to ensure the surgical effect, to reduce the occurrence of complications, and to improve the quality of life of patients after surgery. Comparison between traditional treatment methods and single nostril transsphenoidal approach: Single nostril transsphenoidal approach for surgical treatment of pituitary adenoma can remove the tumor more effectively and with higher safety than previous treatment methods such as drug therapy and radiation therapy alone.