The common tests for H. pylori are rapid urease test and carbon 13-urea breath test. If the result is negative, it indicates the absence of H. pylori infection. If the test result is positive, diagnostic significance exists, indicating the presence of H. pylori infection. H. pylori lives in the stomach and duodenum and is currently considered to be closely associated with chronic gastritis, peptic ulcer disease, low-grade malignant gastric mucosa-associated lymphoid tissue lymphoma, and gastric cancer. Patients infected with H. pylori are usually asymptomatic, and some patients are found positive for H. pylori on an occasional physical examination. Treatment should be individualized, using triple therapy containing clarithromycin, such as proton pump inhibitor + clarithromycin, amoxicillin or metronidazole, or quadruple therapy containing bismuth, such as PPI or H2 receptor blocker + bismuth + metronidazole + tetracycline. For patients who test negative for H. pylori, take personal precautions to prevent H. pylori infection. Wash your hands often, brush your teeth regularly, rinse your mouth after each meal, do not eat contaminated food; practice meal sharing to minimize the chance of infection; wash vegetables and fruits before consumption.