Long-term use of estrogen drugs may cause edema, obesity, patients pay attention to regular living, healthy diet, strengthen fitness, can help reduce the degree of obesity. Estrogen drugs to a certain extent can affect the body’s metabolic function, mainly to promote the body’s sodium retention, synthesize a variety of proteins in the liver, long-term use of patients prone to edema, obesity. Patients should pay attention to their health care, and should not refuse to take the drug because of the side effect of becoming fat, because the lack of estrogen is detrimental to human health, which can lead to symptoms such as irregular menstruation, poor skin, poor mental health, and so on. People who no longer need to take estrogen drugs should be gradually discontinued under the guidance of a doctor, and sudden discontinuation of the drug is prone to rebound phenomenon, that is, the original disease recurrence or even aggravation. Easier to get fat hormone drugs are generally glucocorticoids, long-term use of the body prone to the formation of fat accumulation, and even redistribution, the emergence of centripetal obesity, that is, head and face, chest and abdomen, waist and back fat accumulation. If patients do not pay attention to diet and exercise during the drug, it is easy to accelerate obesity, and obesity is more obvious. Generally after stopping the drug, the body metabolism is more stable, and there is no interference of excess hormones, you can then reasonably control the diet and exercise, even if the people who have been obese can also be effective in slimming.