Long-term insomnia: 1, will have an impact on the human vascular system, long-term sleep can lead to vascular spasms, serious time can appear cerebral blood supply symptoms. 2, can also affect the human body’s endocrine, due to insomnia will lead to changes in the level of human hormone secretion, there can be obesity as well as abnormalities in the thyroid function, or abnormalities in the metabolism of glucose leading to diabetes, etc. 3, can also be the memory loss The brain cells do not get enough rest and are in chronic oxygen deprivation, which can lead to memory loss and slow reaction. 4, there can also be cardiac symptoms, due to insomnia can lead to premature beats, and in severe cases there can be frequent ventricular premature beats, arrhythmia, etc. 5, there can also be coronary artery disease, angina pectoris, due to spasm of coronary artery vessels, the patient appears to have heart and myocardial ischemia symptoms.