Goserelin acts similarly to gonadotropin-releasing hormone in humans, and prolonged use will inhibit the secretion of luteinizing hormone by the pituitary gland. When used in men, the drug reduces serum testosterone, thereby alleviating the symptoms associated with advanced prostate cancer. In women, it can lower serum estradiol, so it can treat breast cancer in premenopausal and perimenopausal women, as well as relieve endometriosis. The side effects of the drug need to be noted and it is recommended to use the drug strictly under the guidance of a doctor. I. Side effects: 1. More common side effects: Patients may experience flushing and decreased libido after using the drug. Some patients using Goserelin may cause a decrease in bone density and subsequently osteoporosis. In addition, for female patients may experience excessive sweating, vaginal dryness, breast size changes, etc. Some may also experience headache and depression. Patients with endometriosis may experience irreversible amenorrhea after medication. Male patients may experience breast swelling as well as tenderness, urethral obstruction, spinal cord compression, temporary aggravation of skeletal pain and other reactions. 2. Rare side effects: A few patients may experience mild bruising at the injection site and mild rash, which can generally subside on their own. Very few patients may experience arthralgia, non-specific sensory abnormalities and gastrointestinal symptoms such as abdominal distension, abdominal pain, nausea, vomiting, constipation, diarrhea, etc.; 3. Other: Since goserelin is used to treat related diseases by lowering sex hormones, there may be a risk of depression or mood changes, so patients should inform their doctors immediately when abnormal moods occur. For patients with pituitary adenoma using goserelin, pituitary stroke may occur, so a thorough evaluation by a doctor is required before using the drug. Contraindications and precautions: 1. Contraindicated in pregnant and lactating women: Goserelin may cause abnormal development of the fetus and infants, so it is contraindicated in pregnant and lactating women; 2. Drug allergy: People who are allergic to Goserelin should not use this drug; 3. Other: male patients with urethral obstruction or spinal cord compression tendency should be used with caution. In addition, the use of goserelin for treatment in children is generally not recommended.