Today and we talk about the diphenhydramine class of anti-hypertensive drugs, can be broken open to take?
1.Commonly used diphenhydramine drugs
Mainly including amlodipine, levamlodipine, nifedipine controlled-release tablets, nifedipine extended-release tablets (I, II, III), felodipine extended-release tablets, lacidipine and nifedipine, etc.
2.The classification of commonly used diphenhydramine drugs
In order to achieve the purpose of smoothly lowering blood pressure, long-acting antihypertensive drugs or slow (controlled) release preparations should be used to achieve smooth control of blood pressure and reduce target organ damage.
Commonly used long-acting diphenhydramine: nifedipine controlled-release tablets, nifedipine extended-release tablets III, amlodipine, levamlodipine, felodipine extended-release tablets and lacidipine, which are usually taken only once a day.
Commonly used intermediate-acting diphenhydramine: nifedipine, nifedipine extended-release tablets (I, II), usually taken once a day in the morning and once in the evening.
Commonly used short-acting diphenhydramine class: nifedipine, used 2-3 times a day.
3, the adverse consequences of breaking open to take
If you break, grind or chew the drug that cannot be broken, ground or chewed, it will destroy the structure of the preparation and release the entire dose of the drug instantly, causing a sharp drop in blood pressure and even adverse events such as shock, arrhythmia and impaired consciousness.
4.Time to take the drug
In general, take it in the morning.
5.Drinks to avoid
Avoid eating or drinking grapefruit/grapefruit juice when taking nifedipine, felodipine, lacidipine and nifedipine. Amlodipine is not affected by grapefruit juice.
6. Major adverse reactions
If ankle edema, headache and flushing occur during the use of diphenhydramine anti-hypertensive drugs, it should be considered whether it is related to the use of drugs.
7.Misconceptions of hypertension treatment
Patients with hypertension, be sure to get out of these misconceptions, including.
(1) antihypertensive treatment, blood pressure is normal, stop the drug.
(2) Reluctance to take medication prematurely.
(3) Relying solely on medications and ignoring lifestyle changes.
(4) Only taking medication without looking at the effect.
(5) Using medication based on feelings and estimating blood pressure based on symptoms
(6) Treatment of hypertension by infusion.
(7) The faster and lower the blood pressure is lowered, the better.
(8) Superstitiously believe that “magic pills” can cure hypertension.