The wrist joint is the bridge between the forearm and the hand. It has a complex structure, consisting of eight wrist bones, the distal ulnar radius, five metacarpal bones and complex ligament connections, and can perform flexion, extension, ulnar deviation, radial deviation, rotation and other compound movements. Because of the complex structure of the wrist joint and the variety of movements, the wrist joint is prone to strain and injury when falling, resulting in wrist joint pain. The causes of wrist pain are complex and varied, and the common non-traumatic causes are as follows: 1. Strain-related diseases. Long-term mechanical labor is prone to cumulative injury, resulting in degenerative strain on the wrist joint, leading to joint pain. Many middle-aged and elderly people engaged in domestic work and bringing up children are especially prone to strain line pain of shoulder, elbow and wrist joints. The wrist mostly shows pain on the dorsal side of the radius, and the pain is obvious when clenching a fist and exerting force or wringing a towel. The thumb extensor tendon of the thumb is spanned by the radial-dorsal bone surface of the wrist, and repeated friction can lead to inflammation causing pain. Most of this pain can be controlled by rest, changing lifestyle habits, closure, physical therapy and other treatments. Long-term computer work or playing computer games, the right hand quickly and repeatedly click the mouse, long-term intensive, repeated and excessive activities, resulting in wrist muscle or joint paralysis, swelling, pain, spasm, can lead to “mouse hand” or even “aseptic necrosis of the moon bone”. There is stiffness, pain, numbness and weakness of thumb muscles, wrist joint pain and limited movement of the finger and middle finger. 2, rheumatic diseases. Rheumatic disease is a general term for a large group of connective tissue diseases involving joints and ligaments. Common rheumatoid arthritis, rheumatoid arthritis, systemic lupus erythematosus arthritis, psoriatic arthritis belong to this category of diseases. There are clear diagnostic criteria and standardized treatment plans for these diseases, and they can be well controlled through regular treatment. However, not all joint pain is rheumatism, unexplained joint pain should go to the hospital standardized treatment, do not think it is “rheumatism” indiscriminately take drugs, not only can not achieve the purpose of treatment, but also easily lead to drug damage. 3, wrist joint and peri-articular infection. Infection can occur in the wrist joint and the bones that make up the wrist joint, resulting in wrist pain. Currently, tuberculosis is becoming more and more insidious, and most of them lack typical symptoms of tuberculosis. Only a comprehensive analysis of the patient’s condition, examination and laboratory tests can lead to early diagnosis and treatment. In the case of septic arthritis and osteomyelitis of the wrist joint, the onset of the disease is acute, combined with fever, localized redness, swelling and pressure pain. Early diagnosis and standardized treatment with effective antimicrobial agents can minimize joint damage and preserve joint function. 4.Carpal joint osteopathy, bone tumor. Severe osteoporosis and other metabolic bone diseases can cause bone pain in many parts of the body, including the wrist joint, which requires clear diagnosis and targeted treatment after finding the cause as much as possible. Primary and metastatic tumors of bone can lead to bone destruction and cause pain, so it is necessary to analyze the condition comprehensively, determine the nature of the lesion by combining imaging data and pathological examination, and do targeted treatment.