Hypoechoic nodules in both breasts are often the result of ultrasonography, suggesting the presence of masses and nodules in the breast, which may manifest as breast masses and lumps in the breast area. The probability of nodules in the breast may be benign or malignant, and further improvement of X-ray, magnetic resonance imaging (MRI), pathological tissue biopsy and other examinations are needed to confirm the diagnosis. The following conditions are common: Common causes and treatments I. Benign 1. Breast hyperplasia: Most breast hyperplasia is benign, mostly related to hormonal changes caused by menstruation, pregnancy and other factors, manifested as breast nodules or lumps, often accompanied by Breast swelling and pain or tenderness. These nodules often have no significant impact on the health of patients. If the breast swelling and pain before menstruation is serious, oral ibuprofen and other medications can be taken as prescribed by the doctor. 2. Intraductal papilloma: It is found in the ductal epithelium of the breast and is a benign tumor, often related to ovarian endocrine disorders and elevated estrogen levels. Generally the tumor is small and in most cases not palpable, but it is often accompanied by overflow of blood from the nipple, plasma blood and other traits, which may be the reason why patients seek medical attention. For this disease, surgical treatment is usually chosen, including open surgery, ductoscopic surgery, etc.; 3. Breast fibroids: often mixed by glandular epithelium and fibrous tissue form benign tumors, often causing painless lumps in the patient’s breast, and a few patients may experience breast pain. Other benign nodules: such as breast cysts, breast lipomas, etc., often cause breast lumps, which are generally less likely to become malignant, but need to be alerted when the lumps have unclear boundaries and poor mobility. Second, ultrasound examination of patients with malignant breast cancer, breast sarcoma and other malignant tumors usually also show hypoechoic changes, which are related to various factors such as hormonal changes, family history, and overnutrition, etc. The main manifestation is an immovable lump in the breast, along with nipple depression, which may be accompanied by fluid overflow. Patients with breast cancer are typically characterized by the dimpled nipple dimple sign and orange peel-like changes in the skin around the nipple. Patients with breast sarcoma also often present with significant localized blood vessels in the breast, commonly known as bruising. Early detection of malignant disease and early surgical treatment are also important factors affecting the patient’s prognosis. If patients are clearly diagnosed, they should actively cooperate with the doctor and pay attention to keep the local skin of the breast clean and avoid violent injury during the treatment.