Calcium gluconate tablets can be used in the treatment of urticaria, but they are not effective when used alone and are generally recommended as an adjunct to the treatment of urticaria. Urticaria may be related to immune factors, external causes such as infection, hot and cold stimulation and many other triggers can cause the dilation of small blood vessels in the skin mucosa. The increased permeability of blood vessels can cause inflammatory exudation, localized edema of the skin, etc. The skin may have mass-like changes, often accompanied by itching. Calcium gluconate mainly elevates the concentration of calcium ions in the blood. The elevated calcium ion concentration reduces capillary permeability and reduces tissue fluid exudation, thus reducing edema. Oral calcium gluconate tablets need to be absorbed through the gastrointestinal tract, and the increase in blood calcium ion concentration is often not very obvious or has a slow onset of action, which may not achieve rapid results. Only one symptom of urticaria is treated, which does not play a role in eradicating the cause of the disease, so it is usually chosen as an adjunctive medicine. Urticaria is an allergic disease, mainly based on anti-allergy treatment, you can take oral antihistamines, such as kelthane, levocetirizine hydrochloride tablets, etc., along with the use of calcium gluconate to improve the symptoms.