The treatment principle is to stop the bleeding and adjust the cycle. To stop bleeding: first use high-dose estrogen or a combination of estrogen and progestin. Adopt appropriate preparations and use methods according to the amount of bleeding. 1. Massive bleeding: Require that the effect be seen within 6-8h and the bleeding basically stop within 24-48h. If the bleeding does not stop after 96h or more, the possibility of the presence of organic lesions should be considered. A large amount of estrogen can rapidly promote the growth of the endometrium and stop the bleeding by repairing the trauma within a short period of time, which is also called “endometrial repair method” and is suitable for patients with long bleeding time, large amount and hemoglobin <80g/L. The main drugs are estradiol benzoate, combined estrogens and estradiol valerate. (1) Estradiol benzoate: initial dose 3-4mg/d, maintain if bleeding decreases significantly; if bleeding does not decrease, increase the dose, or start with 6-8mg/L, with the maximum daily dose generally not exceeding 12mg. Start reducing the dose 3 days after bleeding stops, usually by 1/3 every 3 days. (2) Combined estrogen: 25mg, intravenous, can be repeated once in 4-6h, usually 2-3 times; the next day, 3.75-7.5mg/d of combined estrogen (Bemelia) should be given orally, and it is appropriate to reduce the amount by 1/3 every 3 days. Oral contraceptives can also be started within 24-48h. (3) Oral combined estrogen (Bemelia) 1.25mg per d or estradiol valerate (Glaxo) 2mg per d every 4-6 h. After 3 days of hemostasis, it is appropriate to reduce the dose by 1/3 every 3 days. High-dose estrogen hemostasis should be contraindicated in patients with a hypercoagulable state of the blood or a history of thrombotic disease. Progestin must be added after hemoglobin increases to 90 g/L or more to facilitate complete shedding of the endometrium after discontinuation of the drug. If hormone therapy is ineffective or if organic lesions are suspected, the patient and her family should give informed consent and then consider scraping. 2. Small amount of bleeding: Use the lowest effective amount of hormone to reduce drug side effects. The use of progestin-dominant oral contraceptives, such as Mafolone, Mendocin, or Daimler-35, is 1-2 tablets each time, 2-3 times a day, gradually reducing the dosage to 1 tablet a day 3 days after the bleeding stops, and maintaining it until the end of the cycle 21 days after the bleeding stops.