Cerebral amyloid angiopathy is a cerebrovascular disease caused by the deposition of amyloid material in the soft meninges and the middle layers of small cortical arteries. It is clinically characterized by multifocal spontaneous cerebral parenchymal hemorrhage resulting from repeated multi-site vascular rupture. Cerebral amyloid angiopathy is a type of cerebrovascular disease in the elderly, the incidence of which increases with age, with less incidence before the age of 55 and up to 60% above the age of 90. Clinical manifestations 1. Cerebral hemorrhage Hemorrhage caused by cerebral amyloid angiopathy is not related to hypertension and is most common with recurrent multiple lobar hemorrhages. The site of hemorrhage is located in the occipital lobe, occipito-parietal region or frontal cortex and subcortical white matter. 2, dementia 30% of patients with cerebral amyloid angiopathy have symptoms of dementia, manifesting as memory loss, poor computational power, and impaired comprehensive analysis. 3, transient cerebral ischemia and cerebral infarction The internal carotid artery system is predominant, manifesting as transient hemiparesis, hemianesthesia, aphasia; the vertebrobasilar artery is predominant, manifesting as vertigo, tinnitus, ataxia, etc. Diagnosis Elderly patient with no history of hypertension and CT examination showing multifocal cerebral hemorrhage can be diagnosed. Treatment Treatment principles are the same as those of internal medicine, but patients with this disease should avoid anticoagulants and antiplatelet agents during the recovery period.