My father had Parkinson’s in 2004, and as his condition worsened, the pain became worse. Sometimes the pain area is in his thighs and sometimes in his lower abdomen. He just recently had surgery for an inguinal femoral hernia at your hospital, and the most unbearable thing for him is when the painful area rejoins the wound. For this reason, he took a box of ibuprofen extended-release capsules after the surgery (it has been 70 days). I would like to ask Dr. Ge a few questions 1. whether this medicine can be taken for a long time 2. whether the effect of the medicine will be weakened in the long run 3. whether there is any pain relief medicine or injection that works fast 4. what is a better way? The pain department of Beijing Chaoyang Hospital, Gao Xiaodong The pain department of Beijing Chaoyang Hospital, Gao Xiaodong: 1. Ibuprofen is a non-steroidal anti-inflammatory analgesic, which cannot be taken for a long time, and generally cannot be taken continuously for more than 2 weeks. 2. It can cause side effects such as bleeding peptic ulcers, cardiovascular accidents, kidney damage and impaired platelet function. A patient I once consulted was hospitalized for gastrointestinal bleeding due to long-term headache taking Fenbendazole. 3.There is definitely drug tolerance phenomenon when taken for a long time. 4, for Parkinson’s disease caused by pain is really not too good treatment, now can only be symptomatic treatment to maintain!