Tremor is a rhythmic, involuntary movement of one or more functional areas of the body. I. Clinical classification: 1, idiopathic tremor (also known as familial tremor) is the most common type of tremor, associated with central nervous system function abnormalities; 2, Parkinson’s disease tremor neuropathological changes are more clear; 3, cerebellar tremor related to the cerebellum and brainstem; 4, midbrain tremor. Clinical manifestations: resting tremor, locomotor tremor, postural tremor, intentional tremor. 1, surgical treatment: for part of the tremor drug treatment is ineffective, and with the long-term medication, side effects gradually increase difficult to adhere to the medication patients, can consider surgery. 1954 foreign Hassler and Reichert, etc. The first application. Modern stereotactic microelectrode surgery is characterized by minimally invasive, safe and reliable: (1) microelectrode recording; (2) electrical impedance measurement; (3) variable-frequency (2-3Hz,100Hz) variable voltage, current, wave width microelectrical stimulation; (4) experimental reversible destruction. It can rapidly and accurately locate the site, size, volume, shape of intracranial lesions, and the relationship with the surrounding important brain tissues (internal capsule, optic tract, etc.), and can rapidly and accurately destroy intracranial foci with radiofrequency thermo-coagulation, and balance and repair the neurological network, commonly used targets: ventral intermediate nucleus of the thalamus (Vim), and the medial part of the globe of pallidum (GPi), and for the economically well-off patients, they can choose to stimulate the target point of the brain with DBS. For patients with good economic conditions, DBS can be chosen to stimulate the target points in the brain. The latest combined program 1: the group of nerve repair drugs and efficient pathway treatment can increase the efficacy, delay neurodegeneration and aging, and reduce the recurrence of the disease. The latest combined program 2: the combination of cell transplantation-neural repair surgery can increase the efficacy, delay aging and recurrence of the disease. 67%, post-traumatic tremor 51%. The complication rate is generally 0.5% to 26%, and the case fatality rate is generally less than 1%. The average duration of surgery was 1 hour. Most of the patients were able to eat fluids 2-4 hours after surgery. On the next day after surgery, those with mild preoperative conditions can get out of bed. If the patient has severe trunk symptoms, bilateral surgery is usually required. The interval between surgeries is about several weeks-6 months. The cost of hospitalization is about 35,000 to 40,000 yuan. The length of hospitalization is about 10 days.